RUMORED BUZZ ON CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most recently, it's been identified that conolidine and the above mentioned derivatives act about the atypical chemokine receptor 3 (ACKR3. Expressed in similar areas as classical opioid receptors, it binds to some wide array of endogenous opioids. As opposed to most opioid receptors, this receptor functions as a scavenger and does not activate a 2